Dabigatran is considered as an oral prodrug that can be metabolized by serum esterase to required product. It is a synthetic, reversible and competitive direct thrombin inhibitor. The thrombin inhibition interrupts with coagulation cascade, thus inhibiting the formation of clots. Moreover, this is also used for decreasing the chances of venous thromboembolic occurrence in patients those gone for hip or knee replacement surgery. Therefore, by inhibiting the free thrombin, fibrin bound thrombin and thrombin induced platelet aggregation, this medicine shows it action.
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