In medical term, Lercanidipine acts as calcium channel blocker, belonging to the category of dihydropyridine. It is used alone or in combination with angiotensin-converting enzyme inhibitor. Thus, it is used in the management of hypertension, Prinzmetal variant angina and chronic stable angina pectoris. It inhibits ion-control gating mechanism and hinder with the discharge of calcium from sarcoplasmic reticulum. Additionally, this medicine also blocks the influx of extracellular calcium available across myocardial smooth muscle cells.
Due to its wide action, this lowers down blood pressure.
2,N-Dimethyl-N-(3,3-Dipheny- lpropyl)-1-Amino-2-Propanol work as a key pharmaceutical intermediate that works as an antagonist of L-calcium channels. Thus, it is used in the treatment of angina and coronary disease.
Processing the 2,6-Dimethyl-5-Methoxycarbonyl-4-(3-Nitro- phenyl)-1,4-Dihydropyridine-3-Carboxylic Acid in accordance with international quality standards, it is used as an intermediate for processing of Lercanidipine.